Issue Number 7 Straight Talking 40 A New Formula for IT Success 64 Fostering Incremental Innovation to Drive Business Value Paul Cassidy CIO, Merck Animal Health Head of IT Strategy, Shire Pharmaceuticals Intuitive to Data-Driven Decision 46 From Making the Regulators Have a Say in IT 70 When Governance Hugh Banister Len De Villiers Dave Williams CIO, Santos 52 The ROI of Taking Career Chances Larry A. Pickett, Jr. VP and CIO, Purdue Pharma 58 Group CIO, Telkom South Africa Big Thinking Leading Digital The Excitement of Leading Transformative Change Ursula Soritsch-Reiner CIO, Sulzer George Westerman 78 Principal Research Scientist, MIT Sloan Initiative on the Digital Economy, and co-author of Leading Digital: Turning Technology into Business Transformation